Since the synthesis of pharmaceuticals in the pharmaceutical industry does not produce any undesirable side-effects or permit germs to enter the product, the purity requirements for the process and the product are especially high. The pharmaceutical industry consists of a wide range of applications and processes, all of which have specific requirements. The manufacturing of finished pharmaceuticals, for instance, requires excellent chemical resistance of sealing materials to various educts and solvents. Extremely low temperatures can occur in the production of vaccines or proteins and in the separation of blood, which requires seals that are very resistant to cold temperatures. These and numerous different requirements present sealing solutions in the pharmaceutical industry with new difficulties consistently.